Developing a sperm morphology test which would not need cell fixation and staining, instead the sperm shape and size are automatically assessed on a fresh immobilized sample at multiple focus depths. This system accesses Head, Neck Piece and track the tail for abnormalities. When the technology is ready, validation trials will be undertaken t o compare the results with current manual methods and by measurement of specimens which are used in assisted conception procedures e.g., in-vitro fertilization (IVF) and intrauterine insemination (IUI).
Computer Aided Sperm Analysis Principal Investigator: Dr. Asad Naeem
ICT RnD Funded
A commercial application that performs repeatable and accurate analysis of human spermatozoa by automatically finding each sperm and then tracking individual sperm to calculate its displacement accurate to the nearest micrometers using high speed cameras mounted on microscopes. The application is intended for over 250 fertility clinics only in UK, not to mention pathology labs. Dr. Tomlinson Matthews (Head of Andrology Department, Queens Medical Center, Nottingham, UK) collaborated and Dr. Matthews sent medical test equipment to Pakistan for testing and development worth around 8000 GBP already. Automated computer aided sperm analysis system validated properly in clinical trials. The clinical trials were held at University of Nottingham Hospital, University of Liverpool and University of Cambridge. [Visual Studio 2010, C#, Access, Unity, Wix, AForge library, Unibrain and PointGray camera SDKs]